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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Brevilin A Influence on cell morphology Confocal microscopy- DAPI 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on cell cycle Flow cytometry 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on cell cycle proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on cell cycle proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on cell cycle proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on cell cycle proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on cell cycle proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on apoptotic proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on apoptotic proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on apoptotic proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on apoptotic proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on apoptotic proteins Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens p-STAT3
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens STAT3
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on tumor growth Average tumor volume 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on tumor growth Average tumor weight 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on tumor growth Average mouse body weight 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude p-STAT3
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude STAT3
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on STAT3 signalling MTT 10.00 µM A549R Homo sapiens
Brevilin A Influence on STAT3 signalling Luciferase Assay 10.00 µM A549R Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens pTyr705-STAT3
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens STAT3
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens pTyr705-STAT3
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT3
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens